DNA phosphorothioate modification is a distinctive epigenetic alteration in which a non‐bridging oxygen atom within the DNA sugar-phosphate backbone is replaced by ...

A UCLA-led study has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin — DNA and proteins — plays a critical role.

The goal of gene therapy is to permanently cure hereditary diseases. One of the most promising technologies for this is the ...

An important DNA modification is methylation, or the addition of a methyl group to the 5th carbon of cytosine. This forms 5-methylcytosine (5mC), typically associated with repression of gene ...

Scientists injected a fragment of 40,000-year-old genetic material into laboratory mice, revealing skeletal changes from a ...

DNA is often seen as the blueprint of life—carrying the code to govern the development and traits of an organism—but “there are things beyond the DNA sequence,” says Xiaoqi Feng, a plant geneticist at ...

With advances in genomics, scientists are discovering additional components of the DNA alphabet in animals. Do these unusual chemical modifications of DNA have a special meaning, or are they just ...

Scientists are researching ways to genetically modify plants and animals to be more resistant to threats like climate change.

Scientists discovered four protein changes that help naked mole rats repair DNA faster. These small tweaks may explain their ...