Despite the significance of immune checkpoint inhibitors (ICIs) in solid tumor treatment, identifying ICI-sensitive populations remains a challenge. Mutations in DNA damage response (DDR) pathway ...
Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells. The research, published today as a Reviewed Preprint in eLife, is described by the editors as a ...
Yuan He aims to understand how cells read and repair their genomes. His research encompasses two primary areas: transcription, in which genetic information is copied from DNA into messenger RNA, and ...
Scientists discovered four protein changes that help naked mole rats repair DNA faster. These small tweaks may explain their ...
Researchers at Spain’s CNIO have mapped 20,000 distinct DNA repair “scars,” building the first human REPAIRome. This atlas reveals how each human gene shapes DNA repair after double-strand breaks.
Naked mole rat's unique DNA repair mechanism may hold key to longevity and age-related research breakthroughs.
Daegu Gyeongbuk Institute of Science and Technology (DGIST; President Kunwoo Lee) announced that a research team led by Professor Younghoon Kee from the Department of New Biology has successfully ...
What naked mole-rats lack in the looks department they make up for it in longevity, living healthily for nearly four decades.
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